hrp0082p2-d1-595 | Thyroid | ESPE2014

Papillary Thyroid Cancer with Diffuse Pulmonary Metastasis: How to Manage?

Bas Serpil , Abali Saygin , Gokdemir Yasemin , Haliloglu Belma , Atay Zeynep , Karadag Bulent , Bereket Abdullah , Turan Serap

Background: Papillary thyroid cancer (PTC) is the most common endocrine malignancy in children. PTC shows more aggressive progress in children than in adults in respect to local and distant metastases. Here we presented a PTC case with primary pulmonary symptoms and pulmonary metastasis.Case: A 15.5-year-old male patient presented to the clinics with cyanosis and respiratory difficulty for the last 2 years. He had dyspnea, central cyanosis, clubbing, and...

hrp0082p2-d1-290 | Bone | ESPE2014

Sleep-related Breathing Disorders in Pycnodysostosis

Turan Serap , Atay Zeynep , Gokdemir Yasemin , Bas Nilay , Haliloglu Belma , Abali Saygin , Bas Serpil , Ersu Refika , Bereket Abdullah

Background: Pycnodysostosis is an autosomal recessive disease characterized by short stature, osteosclerosis, increased bone fragility. In these patients maxillary and mandibular hypoplasia, flattening of the mandibular angle, long soft palate, narrow palate structure can lead to pharyngeal narrowing and obstructive sleep apnea syndrome (OSAS).Objective and hypotheses: Our aim was to evaluate sleep disordered breathing in children with pycnodysostosis.</...

hrp0095p1-445 | Diabetes and Insulin | ESPE2022

Glucagon Response to Hypoglycemia During Extended Oral Glucose Tolerance Test in Children with Cystic Fibrosis and Comparing with Healthy Peers

Haliloglu Belma , Seven Menevse Tuba , Gürpınar Tosun Busra , Guran Tulay , Turan Serap , Ispir Turgay , Gokdemir Yasemin , Erdem Ela , Bereket Abdullah

Post-OGTT hypoglycemia is common in Cystic Fibrosis(CF). The aim of the study is to determine of the role of glucagon in the pathogenesis of hypoglycemia in CF patients. A 3-hour-OGTT was performed fifty-three subjects (44CF,9 age-matched controls). Sixteen (36.4%) subjects had normal glucose tolerance (NGT), 13 (29.5%) had isolated hypoglycemia (IsoHypo), 8 (18.2%) had hypoglycemia with abnormal glucose intolerance (Hypo+AGT), 5 (11.4%) had AGT and 2 (4.5%) had CFRD. After AG...